Biological Weapons Research

Anthropic disclosed five instances in which researchers used Claude for work related to biological weapons, viruses, and toxins. The cases involved:

  • Chikungunya virus—gain-of-function research to enhance transmissibility and immune evasion
  • Highly pathogenic avian influenza—experiments to adapt it to mammals
  • Orthopoxviruses (the family that includes smallpox and mpox)
  • Venom peptides and toxins—computational redesign of dangerous proteins

Anthropic stressed that it’s not claiming the scientists intended harm. “The same information that can be used to develop a biological weapon could also be used to develop, for example, a vaccine or a cure for a disease”.

Surveillance and Espionage

The report also found cases involving:

  • Iranian actors who developed a system capable of identifying people through their social media accounts
  • A contractor working for Malian national security authorities who allegedly used Claude to develop software for an intelligence-gathering operation
  • A Russia-linked cyber espionage campaign that used Claude to automatically rewrite malware to evade detection

Anthropic said these cases point to a broader shift in how AI can be used in state-linked operations. “AI is now being used in place of an engineering workforce”.

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